Sustanon 250 product was developed by Organon as an ideal HRT (Hormone Replacement Therapy) solution, and it was thought at the time that the different esters would be able to provide a constant release of Testosterone over a months time. Sustanon is a blend of different estered testosterones (4 of them): testosterone propionate - 30 mg, testosterone phenylpropionate - 60 mg, testosterone isocaproate - 60mg, and testosterone decanoate -100 mg.
This drug was highly sought after as a "superior" version of testosterone in the late 80´s and through the mid 90´s. No doubt this is partly due to the very nice write-up Dan Duchaine gave it in his newsletters. However, lets keep in mind that this drug was designed for convenience, not athletics or bodybuilding. The advantage to this drug, according to the manufacturer, is that it can be injected once a month, and the different esters would provide different timed releases over that month, and the patient would therefore only need to visit the doctor once a month for his shot. For athletes or bodybuilders (who routinely use between half a gram and a gram of testosterone per week), this product is really no better than any other form of injectable testosterone.
Lately, it seems that this product has fallen out of favor with Steroid members, as many feel that the inclusion of the Propionate and phenylpropionate estered forms of testosterone in this blend would necessitate shooting every other day. This stems from the fact that testosterone propionate would be shot every other day at least, and testosterone phenylpropionate would generally be shot every third day.
Sustanon will do exactly what other forms of testosterone will do:
Testosterone will cause both muscle growth as well as fat loss. It sends a message to muscle cells to store more contractile protein (called actin and myosin), thus making your muscles grow. It also protects your muscles from catabolic (muscle wasting) glucocorticoid hormones(1). Thus it is often said that testosterone is not only anabolic, but it is strongly catabolic. Not only does it cause an increase in size of the muscle fibres (hyperfascia) but it also can change the appearance and the actual number of muscle fibres (Hyperplasia)(2). Testosterone has the ability to increase erythropoiesis (red blood cell production) in your kidneys(4), and a higher Red Blood Cell (RBC) count may improve endurance by producing more highly oxygenated blood. More RBCs can also improve recovery from strenuous physical activity. Agression levels often rise dramatically with the use of any exogenous testosterone (3). Testosterone improves muscle contraction by increasing the number of motor neutrons in muscle(5) and improves neuromuscular transmission(6). It also promotes glycogen synthesis(7)
And, since Sustanon is simply a form of (well actually 4 forms of) testosterone, we also know that administration of this compound will produce a dose respondant curve. (10)A what? Yeah...basically a "dose respondant curve" is the fancy way of saying "the more you take, the bigger you get..."
This is true of Sustanon as well as for every form of testosterone, up to a point.
Unfortunately, Sustanon will also do all of the bad things that any form of testosterone is known for:
It will convert to the female hormone estrogen (via a mechanism known as aromatization) by the (you guessed it) aromatize enzyme. Excessive estrogen can lead to unwanted side effects, such as acne, the growth of breast tissue (gynecomastia), fat gain and reduced fat breakdown, loss of sex drive, testicular shrinkage and water retention. Water retention can increase blood pressure weakening blood vessels over time. Unfortunately, this isn´t all it does& it can also interact with the 5 alpha-reductase enzyme. This interaction converts the testosterone to Dihydro-testosterone (DHT), a more androgenic form of the parent hormone. DHT has a high binding affinity to the tissues of the scalp resulting in hair loss in loss in users who suffer from male pattern baldness. DHT can affect the prostate as well, making it larger. This swelling can cause the gland to press against the bladder causing urinary problems. Drugs called 5alpha-reductase inhibitors can prevent these symptoms without blocking testosterone´s anabolic effects.(8) Higher dosages of test can also negatively impact cholesterol, lowering HDL(9). Testosterone is probably the safest steroid around, but it can´t be taken lightly, and Sustanon is no different.
The principal drawback to Sustanon is it´s cost. It can cost between $5 an ampule and $12 an ampule. Compared with Omnadren, Testoviron, or even Sten (other testosterone products featuring various blends of Testosterone), the cost makes it prohibitive. An equal amount of an of the aforementioned products can be had for less than half the average cost of an amp of Sustanon. Sustanon, therefore, is no better or worse than any other form of testosterone... if the price is right.
17b-hydroxy-4-androsten-3-one Testosterone base + 4 different esters Propionate, Phenylpropionate, Isocaproate, Decanoate Formula (base): C27 H40 O3 Molecular Weight (base): 288.429 Molecular Weight, Esters: Propionate: 362.5082 Phenylpropionate: 438.6058 Isocaproate: 404.5886 Decanoate: 460.6958 Formula (base): C19 H28 O2 Melting Point (base): 155 Manufacturer: Organon Effective Dose (Men): 500-2000mg/ week Effective Dose (Women): Not recommended Active life: Up to 3 weeks Detection Time: 3+ months Anabolic/Androgenic ratio:100/100
Celebrex Celebrex is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Celebrex works by reducing substances that cause inflammation, pain, and fever in the body.
Celebrex is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celebrex is also used to reduce the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), to treat acute pain, and to treat pain associated with menstruation.
Before taking Celebrex, tell your doctor if you:
- smoke
- drink alcohol
- have an ulcer or bleeding in the stomach
- have liver disease
- have kidney disease
- have coronary artery disease (CAD)
- have arteriosclerotic disease (hardening of the arteries, clogged or blocked arteries)
- have asthma
- have congestive heart failure
- have fluid retention
- have heart disease
- have high blood pressure
- have a coagulation (bleeding) disorder or are taking an anticoagulant (blood thinner) such as warfarin (Coumadin);
- are taking a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others
There are no restrictions on food, beverages, or activity while taking Celebrex unless otherwise directed by your doctor.
Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.
serious side effects:
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
less serious side effects:
- flatulence or diarrhea
- dizziness
- headache
- insomnia.
Before taking Celebrex, tell your doctor if you are taking any of the following drugs:
- aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, Bayer Select Backache Formula, others);
- an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen
- a diuretic (water pill) such as furosemide (Lasix), hydrochlorothiazide (HydroDiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Hygroton, Thalitone), and others
- an angiotensin-converting-enzyme inhibitor (ACE inhibitor) such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), and others;
- a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others
- an anticoagulant (blood thinner) such as warfarin (Coumadin)
- lithium (Eskalith, Lithobid, others)
- fluconazole (Diflucan)
Celebrex is used to:
Relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis in adults.
ViagraSildenafil citrate, sold under the names Viagra. Viagra pills are blue and diamond-shaped with the words "Pfizer" on one side and "VGR xx" (with xx representing 25, 50 or 100, the dose of that pill in milligrams) on the other. Its primary competitors on the market are tadalafil (Cialis), and vardenafil (Levitra).
As with all prescription drugs, proper dosage is at the discretion of a licensed medical doctor. The dose of sildenafil is 25 mg to 100 mg taken once per day between 30 minutes to 4 hours before sexual intercourse.
It is usually recommended to start with a dosage of 50 mg and then lower or raise the dosage as appropriate. The drug is sold in three dosages (25, 50, and 100 mg).
Contraindications include:
When taking nitric oxide donors, organic nitrites and nitrates, such as glyceryl trinitrate, sodium nitroprusside, amyl nitrite ("poppers")
In men for whom sexual intercourse is inadvisable due to cardiovascular risk factors
Severe hepatic impairment (decreased liver function)
Severe impairment in renal function
Hypotension (low blood pressure)
Recent stroke or heart attack
Hereditary degenerative retinal disorders (including genetic disorders of retinal phosphodiesterases)
Amongst sildenafil's serious adverse effects are: priapism, severe hypotension, myocardial infarction, ventricular arrhythmias, sudden death, stroke and increased intraocular pressure.
Common side effects include sneezing, headache, flushing, dyspepsia, prolonged erections, palpitations and photophobia. Visual changes including blurring of vision and a curious bluish tinge have also been reported.
Care should be exercised by patients who are also taking Protease inhibitors for the treatment of HIV. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side-effects. It is recommended that patients using protease inhibitors limit their use of sildenafil to no more than one 25-mg dose every 48 hours.
Some Viagra users have complained of blurriness and loss of peripheral vision.
A small number of men have lost eyesight in one eye some time after taking Viagra, Cialis, or Levitra. This type of vision loss is called non-arteritic anterior ischemic optic neuropathy (NAION). NAION causes a sudden loss of eyesight because blood flow is blocked to the optic nerve.
We do not know at this time if Viagra, Cialis, or Levitra causes NAION. NAION also happens in men who do not take these medicines. People who have a higher chance for NAION include those who:
have heart disease
over 50 years old
have diabetes
have high blood pressure
have high cholesterol
smoke
have certain eye problems
XenicalBrand name for orlistat, Xenical is a wonder drug for people suffering with obesity and fat related syndromes. A potent member of Lipase inhibitor group of drugs, Xenical helps reduce unwanted weight and also maintain the sliced weight from rising up the scales again. Xenical stops the human digestive system from digesting and absorbing certain fat taken through food. This, however, nullifies the chances of calories settling down on the body. Xenical can show results only when it is taken in with controlled and fat free diet. The most beneficial part of Xenical is that it doesn't stop working after it has reduced the weight. It is equally active in maintaining the lowered weight and thus protects the body from getting affected with other obesity related syndromes. Although much safer from other weight reducing drugs available in the market, Xenical has many side effects. So it is in the interest of the users to take this drug regularly on time for the best results.
Xenical Warnings
The effectiveness and dosage of Xenical may vary from person to person depending on the health conditions. Let your doctor know if you are allergic to any Lipase Inhibitor or Xenical in particular. Also don't forget to mention if you are already suffering from any of the following diseases:
High Blood Sugar;
Chronic mal-absorption syndrome;
Gallbladder problems;
Kidney stones;
Anorexia;
Bulimia.
Enlisted in FDA pregnancy category B, Xenical is not expected to cause any severe damage to growing foetus. This drug has not yet been studied on pregnant women, but cause reduction in the amount of vitamins absorbed by our body through food. It is not known whether Xenical passes into mother's breast milk or not. However, women should always consult a doctor before taking up Xenical during pregnancy or breast-feeding stage.
Xenical have not been tested on children and older adults so far. Doctors are, however, not suspecting any harmful effects of this drug on children and aged individuals.
Xenical may not work at its best with all other OTC or prescribed drugs. So it is recommended to tell your doctor before hand if you are taking any of the following drugs before taking up Xenical:
Neoral;
Sandimmune;
Coumadin;
Lipitor;
Baycol;
Lescol;
Mevacor;
Pravachol;
Zocor.
Xenical Side Effects
Intake of Xenical is followed by the appearance of a host of side effects. Although side effects disappear within 2 to 3 days of usage, it is always safer to consult a doctor immediately after the side effects start surfacing. The serious side effects of Xenical include breath trouble, closed throat, swollen lips, tongue, or face etc.
Side effects like fever, body ache, cough, headache, running nose, sneezing, sore throat gas formation with loose motion, oily stool discharge, orange or brown colored oil in your stool are very common and less harmful. . .
Among the uncommon side effects of Xenical, blood in urine, hearing difficulty, urination problem, dental problem, sudden tension, change in menstrual cycle, rectal pain and uneasiness are notable.
Xenical Overdose
So far no cases of Xenical overdose with fatal consequences have been reported. However, prevention is always better than cure. Avoid taking double dose and rush to a doctor immediately after you realize that you have taken a double dose. This is more important as nothing is known about the normal symptoms of Xenical overdose.
Missed dose of Xenical may not be much harmful. Take the missed dose within one hour after a meal. And if you don't remember within 1 hour just skip the last dose and go for the next scheduled one. Be very careful not to take a double dose.
Xenical Usage Guidelines
Rely on your doctor for the best usage guidelines. Normally Xenical is taken in with a full glass of water. Xenical is taken within one hour of the main meal. Make sure not to include more than 30% of fat in your meal. As Xenical may reduce vitamin absorption power of the body, be very careful and particular about taking vitamin supplements prescribed by the drug. Store Xenical at room temperature for best results.
SolcoserylSolcoseryl Jelly:
Skin and mucous tunic regenerating action. Indications: burns, ulcers and venous insufficiency.
Solcoseryl® Jelly:Suitable for wet wounds.
Apply Solcoseryl® Jelly 2-3 times a day until fresh skin tissue has formed. Improves metabolism and accelerates the regeneration of the tissue in cases of surface ulcers.
Contains:
Free of protein extract of cattle blood.
To date no side effects have been observed. After application of Solcoseryl® Jelly an unpleasant stinging may occur for a short time.
Solcoseryl® Ointment:
Suitable for dry wounds. Continue with Solcoseryl® Ointment to obtain complete epithlisation.
Solcoseryl ointment:
Solkoseril is an extract of the cattle blood, but is free of protein. This product improves the metabolism and accelerates of the regeneration of the tissue in cases of surface ulcers caused by oxygen deprivation, gangrene, bedsores, burns, radiation ulcers, and skin grafts.
Recommended dosage:
In cases of bedsores apply gel until a scab emerges and then use ointment until the new skin surface appears. For burns use either gel or ointment. Normal course of treatment depends on the body's healing process, but usually lasts from 4 to 8 weeks. Use of the gel may irritate or burn the skin, but these side effects do not require interruption of therapy.
RoaccutaneHow does it work?
Roaccutane capsules contain the active ingredient isotretinoin. (NB. Isotretinoin capsules are also available without a brand name, ie as the generic medicine.) Isotretinoin belongs to a group of medicines known as retinoids, which are derivatives of vitamin A. Isotretinoin taken by mouth works by reducing the production of the skin's natural oil (sebum).
Acne occurs due to an excessive production of sebum from over-active sebaceous glands in the skin. The sebum blocks the sebaceous glands, which prevents the oil from flowing freely out and causes an accumulation of sebum under the skin. The bacteria associated with acne thrive in these conditions. They feed on the sebum, and produce waste products and fatty acids that irritate the sebaceous glands, making them inflamed and causing spots.
Isotretinoin decreases the size and activity of the sebaceous glands in the skin, which reduces the amount of sebum that is produced. This stops the glands becoming blocked, and means bacteria are less likely to thrive. It also reduces the inflammation in the skin.
Isotretinoin can have serious side effects and its use must be supervised by a dermatologist. It is reserved for the treatment of severe acne (such as nodular or conglobate acne or acne at risk of permanent scarring) that has not improved with standard treatment involving oral antibiotics and topical medicines.
Your acne may worsen at the start of treatment, but this usually subsides within 7 to 10 days of continued treatment. In most cases, complete or near-complete clearing of acne is achieved with a 12 to 16 week course of treatment, and you are likely to remain free of acne for a long time. Repeat courses are not normally recommended, unless a definite relapse is seen after treatment is stopped. Repeat courses should not be started until at least eight weeks after stopping treatment, as your acne may still improve in this time.
What is it used for?
Severe acne that has not responded to standard treatment with oral antibiotics and topical medicines.
Warning!
Isotretinoin causes major birth defects (serious malformations of a developing foetus) if taken during pregnancy. For this reason your doctor will not prescribe the treatment to women who could get pregnant, unless the following criteria are met: At least one, but preferably two (for example the pill and condoms), effective methods of contraception must be used at all times to prevent pregnancy. Contraception must start at least four weeks before starting treatment, be used at all times during treatment and for at least four weeks after stopping treatment, even if you don't have a period. Your doctor cannot prescribe isotretinoin until you have been using effective contraception for at least a month and have had a negative pregnancy test. Your doctor is only allowed to prescribe 30 days supply of isotretinoin at a time. You will need to have a follow-up visit every month, at which you will have to have a negative pregnancy test before a new prescription can be issued. Five weeks after stopping treatment you should have a final pregnancy test to make sure you have not fallen pregnant. If you think there is a chance you could be pregnant, either during treatment, or in the first month after stopping treatment, you must consult your doctor immediately.
There is no evidence to suggest that children fathered by men who are taking isotretinoin will be affected by the medicine, but men should remember not to give this medicine to anyone, particularly females.
You should never give this medicine to another person and you should return any unused medicine to your pharmacist at the end of treatment.
People taking this medicine must not donate blood during treatment, and for at least four weeks after stopping treatment. This is due to the potential risk of the medicine to an unborn child if the blood transfusion was received by a pregnant woman.
This medicine may cause depression, anxiety, mood changes, psychotic symptoms and rarely suicide attempts. For this reason, if you start to feel depressed, or experience any other mood changes during treatment, it is important to talk to your doctor.
You should avoid exposing your skin to intense sunlight or UV light while taking this medicine. You should use a sunscreen of at least SPF 15 when necessary.
Isotretinoin is likely to make your skin and lips very dry, so it is recommended that you use a moisturiser and lip balm from the start of treatment.
You should avoid waxing any part of your body while taking isotretinoin, and for at least six months after stopping treatment, as this could cause stripping of the top layer of skin. Chemical dermabrasion and cutaneous laser treatment should also be avoided during treatment with isotretinoin and for five to six months after stopping treatment, as this could cause scarring.
Isotretinoin can make your eyes dry. This can be relieved with artificial tear drops. Ask your doctor or pharmacist for advice. If you wear contact lenses you may find that they become uncomfortable during treatment and you have to wear glasses instead. Decreased night vision may also occur during treatment and after treatment has been stopped, and can occur suddenly. For this reason you are advised to be cautious when driving or operating any vehicle at night. If you experience any visual difficulties, inform your doctor so that your vision can be monitored. It may sometimes be necessary to stop treatment.
You will need to have a blood test to monitor your liver function before you start treatment with this medicine, one month after starting and then at further three-monthly intervals.
The amount of lipids (fats such as cholesterol) in your blood should also be monitored before treatment, one month after starting treatment and at three-monthly intervals. If your blood level of triglycerides becomes too high, your isotretinoin dose may need to be reduced and you may have to go on a low fat diet. If your triglycerides cannot be controlled, you may have to stop treatment with isotretinoin.
This medicine may increase your blood sugar level. People with diabetes may need to monitor their blood sugar more frequently during treatment with this medicine. Ask your doctor for advice.
If you experience severe bloody diarrhoea during treatment with this medicine you should stop taking it and consult your doctor immediately.
This medicine is not recommended for children under 12 years of age.
Use with caution in
Women who could get pregnant
History of depression
Decreased kidney function
Alcoholism
Diabetes
Obesity
Lipid metabolism disorders
Not to be used in
Pregnancy
Breastfeeding
Woman who could get pregnant, unless the criteria described in warnings above are met
Acne that has developed before reaching puberty (prepubertal acne)
Decreased liver function
High levels of fats
A condition resulting from the excessive consumption of vitamin A (hypervitaminosis A)
People taking tetracycline-type antibiotics
Peanut or soya allergy (Roaccutane capsules contain arachis oil and soya oil)
Rare hereditary problems of fructose intolerance (Roaccutane capsules contain fructose)
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Isotretinoin MUST NOT be used during pregnancy as it causes major birth defects and serious malformations of the foetus. Women who could get pregnant will only be prescribed this medicine if all the criteria listed in warnings above are met. At least one and preferably two effective methods of contraception must be used to prevent pregnancy for at least one month before starting treatment, during treatment and for at least one month after finishing treatment. If you think you could be pregnant at any point during treatment or in the month after stopping treatment you must consult your doctor immediately.
This medicine must not be used by breastfeeding mothers, as it passes into breast milk and could have adverse effects on the nursing infant. Seek medical advice from your doctor.
Label warnings
Follow the printed instructions you have been given with this medication.
Take this medication with or after food.
TempalginIndications:
Mild to moderate pain of variable origin: headache; migrene; toothache; neuralgia; neuritis; plexitis; lumbalgia; myalgia and myositis; trauma; postsurgery interventions and dental procedures; dysmenorrhoea; burning; premedication in the dental practice.
Dosage and administration:
In adults, Tempalgin is used orally in dose of 1 - 2 tablets 3 - 4 times daily. In children over 10 years, the drug is administered in dose of 1 tablet 2 - 3 times daily. The treatment course duration should not exceed 5 to 7 days.
Contraindications:
Hypersensitivity to tempidon, metamizole and other pyrazolone drugs; acute hepatic porphyria and inborn deficiency of glucose-6-phosphate dehydrogenase; aplastic anemia, leucopenia and agranulocytosis; severe kidney and liver diseases; pregnancy; children younger than of 10 years.
Special warnings and precautions:
The drug is used cautiously in patients suffering from liver or kidney diseases. After more prolonged treatment with Tempalgin regular checks of blood count are necessary. In patients suffering from bronchial asthma, pollinosis, Quincke's edema, chronic airway infections or showing hypersensitivity to analgesic and nonsteroidal anti-inflammatory agents, as well as to other drugs or foods, there is a risk of allergic reactions and asthmatic attacks. During lactation the drug should be avoided, because both active ingredients are eliminated in the breast milk. Tempidon decreases the attention concentration and slows the reflexes. Because of this it should be used cautiously in car drivers and in people working with machines.
Drug interactions:
Because of the inhibition of hepatic enzyme systems metabolising drugs, Metamizole effect is potentiated by tricyclic antidepressants (psychophorin, amitriptyline), oral contraceptive agents, and allopurinol. Due to this its biotransformation is slower, and the toxicity is greater. Barbiturates and phenylbutazone are liver enzyme inductors, and they decrease the strength and duration of the metamizole pharmacodynamic effect. Metamizole lowers the plasma cyclosporin levels. Chloramphenicol increases the myelotoxic action of metamizole (additive effect). Alcohol augments the action of both components. Tempidon potentiates the activity of the hypnotic agents, general anesthetics, and narcotic and nonnarcotic analgesics.
Adverse reactions:
Itching, skin rash, urticaria, Stevens-Johnson's syndrome, Layell's syndrome, angioedema, vasomotor disturbances; asthmatic attack, allergic shock; nausea, vomiting, abdominal pain and discomfort, ulcers and bleeding in rare cases. In susceptible patients, agranulocytosis, leucopenia, aplastic anemia, retention of water and electrolytes are possible.
AnalginAnalgin tablets are used for the treatment of pains of different origin and variable intensity: toothache, headache, arthralgia, neuralgia, myositis, mild to moderate visceral pain, high fever, not responding to other drugs.
Analgin is used with increased caution in patients with a history for hypersensitivity to foods and drugs (particularly to analgesic and nonsteroidal antiinflammatory agents) and also in patients suffering from bronchial asthma, Quincke's edema, chronic pulmonary infections. In patients with hypotension and unstable blood pressure, Analgin should not be used parentarally. If Analgin application is quite necessary, the blood pressure and the heart rate should be monitored. In cases of prolonged Analgin treatment, regular blood count checks are necessary (differential count of the white blood cells). The high Analgin doses can influence unfavourably the active attention. Because of this in these cases driving and working with machines are not advised.
Analgin potentiates the analgesic and antipyretic action of the nonsteroidal antiinflammatory drugs. The Analgin effects are potentiated by the tricyclic antidepressants, oral contraceptive agents, allopurinol, alcohol. Analgin decreases the activity of the coumarin anticoagulants and plasma levels of cyclosporin. The enzyme inductors (barbiturates, glutethimide, phenylbutazone) attenuate the Analgin effects. Analgin potentiates the effects of the drugs possessing CNS depressant activity. Concurrent administration with chlorpromazine is related with a risk of severe hypothermia. Analgin can be used in combination with buscolysin, atropin, codein.
StimolSTIMOL (citrulline malate) - oral solution in sachets
Composition of the medicine:
Active ingredient: one sachet contains 50 % citrulline malate solution 2,0 g;
Excipients: purified water, natural sangria orange flavor, NaOH (for pH adjustment).
Pharmaceutical form. Oral solution.
Pharmacotherapeutic group.
Metabolism corrector to treat asthenia. The product belongs to amino acids.
Stimol utilizes lactate, ammonium, stimulates energy release, brings the cell to another energetic level.
Indications:
Symptomatic treatment of functional asthenia :
physical asthenia;
mental asthenia;
post-infectious asthenia:
postoperative asthenia;
asthenia during pregnancy;
senile asthenia,
asthenia of endocrinology origin (diabetic);
sportsmen's asthenia (muscle pain relief after the intensive training);
asthenia and vegetative syndrome by vegetal and vascular dystonia hypotonic type;
alcohol withdrawal syndrome;
sexual asthenia.
Administrate in case of the following symptoms of asthenia: general weakness, emotional lability, chronic tiredness, low capacity for work, drowse. It is recommended to administrate Stimol in case of muscular pain and cramps, resulting from the accumulation of lactate after the heavy training. This product is
recommended for the period of convalescence.
Contra-indications:
Hypersensitivity to any of the component of the product. Stomach and duodenal ulcer.
Warnings:
One sachet contains about 30 mg (1,3 mmol) of sodium to make pH solution 3,3. It must be taken into the account for patients with a salt free diet.
Interactions with other drugs: Not observed.
Methods of administration and dosage:
Children over 6 years: 1 sachet 2 times per day.
Adult and elderly people: 1 sachet 3 times per day.
Recommended duration of treatment - 4 weeks.
Stimol should be taken during meals. The content of sachet should be diluted up to 100 ml by water or sweetened beverages.
Side effects:
Several cases of discomfort in epigastrium without cancellation of administration. Point out to your physician every undesirable effect.
Shelf-life: 3 years.
Do not administrate after expiry date indicated on the box.
Storage conditions: Store at room temperature ( + 15-25°C), keep away from reach of children.
Packing: 18 sachets in aluminum and polyethylene paper in carton box.
Delivery conditions: Without prescription.
PregnylDescription
Chorionic gonadotropin (kor-ee-ON-ik goe-NAD-oh-troe-pin) is a drug whose actions are almost the same as those of luteinizing (loo-te-in-eye-ZING) hormone (LH), which is produced by the pituitary gland. It is a hormone also normally produced by the placenta in pregnancy. Chorionic gonadotropin has different uses for females and males.
In females, chorionic gonadotropin is used to help conception occur. It is usually given in combination with other drugs such as menotropins and urofollitropin. Many women being treated with these drugs usually have already tried clomiphene alone (e.g., Serophene) and have not been able to conceive yet. Chorionic gonadotropin is also used in fertilization (IVF) programs.
In males, LH and chorionic gonadotropin stimulate the testes to produce male hormones such as testosterone. Testosterone causes the enlargement of the penis and testes and the growth of pubic and underarm hair. It also increases the production of sperm.
Although chorionic gonadotropin has been prescribed to help some patients lose weight, it should never be used this way. When used improperly, chorionic gonadotropin can cause serious problems.
Chorionic gonadotropin is to be administered only by or under the immediate supervision of your doctor. It is available in the following dosage form:
Parenteral
Injection (U.S. and Canada)
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For chorionic gonadotropin, the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to chorionic gonadotropin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy - If you become pregnant as a result of using this medicine with menotropins (e.g., Pergonal) or urofollitropin (e.g., Metrodin), there is an increased chance of a multiple pregnancy (for example, twins, triplets).
Children - Chorionic gonadotropin, when used for treating cryptorchidism (a birth defect where the testes remain inside the body), has caused the sexual organs of some male children to develop too rapidly.
Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any prescription or nonprescription (over-the-counter [OTC]) medicine.
Other medical problems - The presence of other medical problems may affect the use of chorionic gonadotropin. Make sure you tell your doctor if you have any other medical problems, especially:
Asthma or
Epilepsy (seizures) or
Heart problems or
Kidney problems or
Migraine headaches - This medication may worsen these conditions.
Cancer of the prostate or
Precocious puberty (a condition that causes early puberty in boys before 9 years of age) - Increases in the amount of testosterone in the bloodstream may make these conditions worse.
Cyst on ovary or
Fibroid tumors of the uterus - Chorionic gonadotropin can cause further growth of cysts on the ovary or fibroid tumors of the uterus
Unusual vaginal bleeding - Irregular vaginal bleeding is a sign that the endometrium is growing too much, of endometrial cancer, or of other hormone imbalances; the increases in estrogen production caused by ovulation can aggravate these problems of the endometrium. If other hormone imbalances are present, they should be treated before beginning ovulation induction
Proper Use of This Medicine
Dosing - The dose of chorionic gonadotropin will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses for chorionic gonadotropin. If your dose is different, do not change it unless your doctor tells you to do so.
The number of doses you receive each day, the time allowed between doses, and the length of time you receive the medicine depend on the medical problem for which you are receiving chorionic gonadotropin.
For injection dosage form:
For treating men with problems related to low levels of male hormones:
Adults - 1000 to 4000 Units injected into the muscle two to three times a week. You may need to receive this medicine for several weeks, months, or longer. If you are being treated for a low sperm count and have been on this medicine for six months, your doctor may give you another hormone medicine (menotropin or urofollitropin injection). You may need to receive both of these medicines together for up to twelve more months.
To help pregnancy occur in women:
Adults - 5000 to 10,000 Units injected into the muscle on a day chosen by your doctor. The dose and day will depend on your hormone levels and the other medicines that you have been using.
For the treatment of cryptorchidism (condition where testes do not develop properly):
Children - 1000 to 5000 Units injected into the muscle two to three times a week for up to ten doses.
Precautions While Using This Medicine
It is very important that your doctor check your progress at regular visits to make sure that the medicine is working and to check for unwanted effects.
For women taking this medicine to become pregnant :
Record your basal body temperature every day if told to do so by your doctor, so that you will know if you have begun to ovulate. It is important that intercourse take place around the time of ovulation to give you the best chance of becoming pregnant. Your doctor will likely want to monitor the development of the ovarian follicle(s) by measuring the amount of estrogen in your bloodstream and by checking the size of the follicle(s) with ultrasound examinations.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some other effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
For females only
More common
Bloating (mild); stomach or pelvic pain
Less common or rare
Abdominal or stomach pain (severe); bloating (moderate to severe); decreased amount of urine; feeling of indigestion; nausea, vomiting, or diarrhea (continuing or severe); pelvic pain (severe); shortness of breath; swelling of feet or lower legs; weight gain (rapid)
For boys only
Less common
Acne; enlargement of penis and testes; growth of pubic hair; increase in height (rapid)
Frequency not determined
difficult or labored breathing; difficulty breathing; flushing of skin; hives or welts; itching of skin; large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs; pain in chest, groin, or legs, especially the calves; redness of skin; severe, sudden headache; skin rash; slurred speech; sudden loss of coordination; sudden, severe weakness or numbness in arm or leg; sudden, unexplained shortness of breath; tightness in chest; unusually warm skin; vision changes; wheezing
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Less common
Discouragement; enlargement of breasts; feeling sad or empty; headache; irritability; lack of appetite; loss of interest or pleasure; pain at place of injection; trouble concentrating; trouble sleeping; tiredness
After you stop receiving this medicine, it may continue to cause some side effects which require medical attention. During this period of time check with your doctor if you notice any of the following side effects:
For females only
Less common or rare
Abdominal or stomach pain (severe); bloating (moderate to severe); decreased amount of urine; feeling of indigestion; nausea, vomiting, or diarrhea (continuing or severe); pelvic pain (severe); shortness of breath; weight gain (rapid)
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
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